Sunitinib, a Novel Therapy for Anthracycline- and Cisplatin-refractory Malignant Pheochromocytoma
نویسندگان
چکیده
منابع مشابه
Courses of malignant pheochromocytoma: implications for therapy.
Survival of patients with metastatic pheochromocytoma that have exceeded 30 years without therapy to reduce tumors have been reported. We reviewed the records of 38 patients with malignant pheochromocytoma who had received 131I-metaiodiobenzylguanidine (131I-MIBG) treatments between 1981 and 1996 to evaluate longevity. Survival from diagnosis to last follow-up exceeded 5 years in 21 of 38 (55%)...
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BACKGROUND Currently, there is no standard treatment for patients with anthracycline and taxane-refractory metastatic breast cancer (MBC). Capecitabine or vinorelbine plus cisplatin is an effective palliative regimen for taxane-refractory MBC. In this study, we analyzed the efficacy and toxicity of sequential therapy with capecitabine followed by biweekly vinorelbine plus cisplatin in 37 patien...
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Pheochromocytoma is a tumor of adrenal medulla, derived from catecholamine producing chromaffin cells. Majority of the patients present with headache, palpitations and sweating. It is diagnosed by 24 hour urinary VMA (Vinyl Mendelic Acid) measurements and localization is done by MRI and 123I MIBG scanning. Treatment is essentially surgical with adequate preoperative blood pressure control. Undi...
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Malignant catatonia is an unusual and highly fatal neuropsychiatric condition which can present with clinical and biochemical manifestations similar to those of pheochromocytoma. Differentiating between the two diseases is essential as management options greatly diverge. We describe a case of malignant catatonia in a 20-year-old male who presented with concurrent psychotic symptoms and autonomi...
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ژورنال
عنوان ژورنال: Japanese Journal of Clinical Oncology
سال: 2009
ISSN: 0368-2811,1465-3621
DOI: 10.1093/jjco/hyp005